ORPHA:454
Acquired ichthyosis
- Body system
- Skin diseases
- Inheritance pattern
- Not applicable
- Typical age of onset
- Adult
- Estimated prevalence
- Unknown (Worldwide)
- Rarity class
- Unknown
About this disease
A rare epidermal disease characterized by rough, dry skin with prominent, plate-like scaling. It is non-hereditary and usually arises during adulthood in the context of a variety of diseases or conditions, like various types of cancer, autoimmune diseases, endocrine disorders, nutritional deficiencies, but also as a side effect of certain medications. Severity depends on the underlying disease or condition.
Definition from Orphanet.
Common signs
- Dry skin
- Pruritus
- Ichthyosis
- Hyperkeratosis
- Palmoplantar keratoderma
- Recurrent skin infections
Learn more
Source: Orphanet (Orphadata), ORPHA:454. Data release 2026-06-23. www.orphadata.com — CC BY 4.0.