ORPHA:58
Alexander disease
Also called AxD
- Body system
- Neurological diseases
- Inheritance pattern
- Autosomal dominant
- Typical age of onset
- All ages
- Estimated prevalence
- <1 / 1 000 000 (Japan)
- Rarity class
- <1 / 1 000 000
ORPHA:58 is classified under "Neurological diseases" in the Orphanet nomenclature.
Common signs
- Macrocephaly
- Intellectual disability
- Seizure
- Spasticity
- Agenesis of corpus callosum
- Hyperreflexia