Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:61

Alpha-mannosidosis

Also called Lysosomal alpha-D-mannosidase deficiency

Body system
Neurological diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Childhood, Infancy, Neonatal
Estimated prevalence
1-9 / 1 000 000 (Europe)
Rarity class
1-9 / 1 000 000

ORPHA:61 is classified under "Neurological diseases" in the Orphanet nomenclature.

Common signs

  • Macroglossia
  • Coarse facial features
  • Hearing impairment
  • Cataract
  • Intellectual disability
  • Global developmental delay