Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:1427

Autosomal recessive otospondylomegaepiphyseal dysplasia

Also called OSMED

Body system
Bone diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Antenatal, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:1427 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Sensorineural hearing impairment
  • Anteverted nares
  • Abnormal joint morphology
  • Abnormal vertebral morphology
  • Disproportionate short stature
  • Depressed nasal bridge