Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:118

Beta-mannosidosis

Also called Beta-mannosidase deficiency

Body system
Bone diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Adolescent, Adult, Childhood, Infancy, Neonatal
Estimated prevalence
1-9 / 1 000 000 (Europe)
Rarity class
1-9 / 1 000 000

ORPHA:118 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Hearing impairment
  • Intellectual disability
  • Seizure
  • Abnormal facial shape
  • Recurrent respiratory infections
  • Hypoplasia of the abdominal wall musculature