Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:1308

C syndrome

Also called OTCS, Opitz C trigonocephaly, Opitz trigonocephaly C syndrome, Opitz trigonocephaly syndrome, Trigonocephaly C syndrome

Body system
Bone diseases
Inheritance pattern
Not applicable, Unknown
Typical age of onset
Antenatal, Neonatal
Estimated prevalence
1-9 / 1 000 000 (Europe)
Rarity class
1-9 / 1 000 000

ORPHA:1308 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Posteriorly rotated ears
  • Smooth philtrum
  • Long philtrum
  • Micrognathia
  • Anteverted nares
  • Short neck