Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:909

Cerebrotendinous xanthomatosis

Also called CTX, Sterol 27-hydroxylase deficiency

Body system
Inborn errors of metabolism
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy, Neonatal
Estimated prevalence
1-9 / 100 000 (Specific population)
Rarity class
1-9 / 100 000

ORPHA:909 is classified under "Inborn errors of metabolism" in the Orphanet nomenclature.

Common signs

  • Visual impairment
  • Juvenile cataract
  • Abnormal enzyme/coenzyme activity
  • Abnormality of finger
  • Intellectual disability
  • Seizure