Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:169079

Cernunnos-XLF deficiency

Also called Cernunnos XLFD, Cernunnos deficiency, Combined immunodeficiency-microcephaly-growth retardation-sensitivity to ionizing radiation syndrome, NHEJ1 deficiency

Body system
Immunological diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:169079 is classified under "Immunological diseases" in the Orphanet nomenclature.

Common signs

  • Microcephaly
  • Bird-like facies
  • Sloping forehead
  • Bulbous nose
  • Convex nasal ridge
  • Growth delay