Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:565624

Combined oxidative phosphorylation defect type 39

Also called COXPD39, GFM2-related combined oxidative phosphorylation defect

Body system
Inborn errors of metabolism
Inheritance pattern
Autosomal recessive
Typical age of onset
Antenatal, Infancy, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:565624 is classified under "Inborn errors of metabolism" in the Orphanet nomenclature.

Common signs

  • Abnormal corpus callosum morphology
  • Abnormal cerebellum morphology
  • Cerebellar hypoplasia
  • Absent speech
  • Bradycardia
  • Poor head control