Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:1659

Dermatoleukodystrophy

Also called Cutis laxa-leukodystrophy

Body system
Skin diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:1659 is classified under "Skin diseases" in the Orphanet nomenclature.

Common signs

  • Hyperkeratosis
  • Thickened skin
  • Intellectual disability
  • Abnormal nervous system morphology
  • Reduced tendon reflexes
  • Hyperreflexia