Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:2926

Digital extensor muscle aplasia-polyneuropathy

Also called Congenital aplasia of the extensor muscles of the fingers and thumb associated with generalized polyneuropathy, Hamanishi-Ueba-Tsuji syndrome, Polyneuropathy-hand defect syndrome

Body system
Neurological diseases
Inheritance pattern
Not documented in Orphadata
Typical age of onset
Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:2926 is classified under "Neurological diseases" in the Orphanet nomenclature.

Common signs

  • Aplasia/Hypoplasia involving the skeletal musculature
  • Skeletal muscle atrophy
  • Muscular dystrophy
  • Impaired pain sensation
  • Abnormal nerve conduction velocity
  • Camptodactyly of finger