Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:226

Dihydropteridine reductase deficiency

Also called Hyperphenylalaninemia due to dihydropteridine reductase deficiency, PKU type 2, Phenylketonuria type 2

Body system
Inborn errors of metabolism
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy, Neonatal
Estimated prevalence
Unknown (Worldwide)
Rarity class
Unknown

ORPHA:226 is classified under "Inborn errors of metabolism" in the Orphanet nomenclature.

Common signs

  • Microcephaly
  • Intellectual disability
  • Global developmental delay
  • Dysphagia