Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:337

Fibrodysplasia ossificans progressiva

Also called FOP, Myositis ossificans progressiva, Stone man syndrome

Body system
Skin diseases
Inheritance pattern
Autosomal dominant, Not applicable
Typical age of onset
Childhood
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:337 is classified under "Skin diseases" in the Orphanet nomenclature.

Common signs

  • Limitation of joint mobility
  • Subcutaneous nodule
  • Abnormal hallux morphology
  • Fused cervical vertebrae
  • Spinal rigidity
  • Abnormal vertebral morphology