Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:2053

Freeman-Sheldon syndrome

Also called Craniocarpotarsal dysplasia, Craniocarpotarsal dystrophy, Distal arthrogryposis type 2A, Freeman-Burian syndrome, Whistling face syndrome

Body system
Neurological diseases
Inheritance pattern
Autosomal dominant, Autosomal recessive
Typical age of onset
Antenatal, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:2053 is classified under "Neurological diseases" in the Orphanet nomenclature.

Common signs

  • Ulnar deviation of finger
  • Chin dimple
  • Camptodactyly of finger
  • Narrow mouth
  • Abnormality of the dentition
  • Hypertelorism