Rare Zebra

Rare disease search prototype built on Orphanet data

← Back to search

ORPHA:73

Gorham-Stout disease

Also called Gorham disease, Gorham syndrome, Idiopathic massive osteolysis, Progressive massive osteolysis, Vanishing bone disease

Body system
Bone diseases
Inheritance pattern
Not applicable
Typical age of onset
All ages
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:73 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Osteolysis
  • Elevated alkaline phosphatase of bone origin
  • Patchy reduction of bone mineral density
  • Torticollis
  • Osteopenia
  • Edema