Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:3322

Hoyeraal-Hreidarsson syndrome

Also called Progressive pancytopenia-immunodeficiency-cerebellar hypoplasia syndrome

Body system
Immunological diseases
Inheritance pattern
Autosomal dominant, Autosomal recessive, X-linked recessive
Typical age of onset
Infancy, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:3322 is classified under "Immunological diseases" in the Orphanet nomenclature.

Common signs

  • Microcephaly
  • Intellectual disability
  • Global developmental delay
  • Cerebellar hypoplasia
  • Failure to thrive
  • Intrauterine growth retardation