ORPHA:740
Hutchinson-Gilford progeria syndrome
Also called HGPS, Progeria
- Body system
- Skin diseases
- Inheritance pattern
- Autosomal dominant, Autosomal recessive
- Typical age of onset
- Infancy, Neonatal
- Estimated prevalence
- <1 / 1 000 000 (Worldwide)
- Rarity class
- <1 / 1 000 000
ORPHA:740 is classified under "Skin diseases" in the Orphanet nomenclature.
Common signs
- Premature skin wrinkling
- Narrow mouth
- Thin vermilion border
- Micrognathia
- Conductive hearing impairment
- Severe failure to thrive