Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:324575

Hyperinsulinism due to HNF1A deficiency

Also called Hyperinsulinemic hypoglycemia due to HNF1A deficiency

Body system
Inborn errors of metabolism
Inheritance pattern
Autosomal dominant
Typical age of onset
Infancy, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:324575 is classified under "Inborn errors of metabolism" in the Orphanet nomenclature.

Common signs

  • Hyperinsulinemic hypoglycemia
  • Neonatal hypotonia
  • Neonatal hypoglycemia
  • Increased C-peptide level
  • Excessive insulin response to glucagon test
  • Decreased circulating free fatty acid level