ORPHA:276238
Machado-Joseph disease type 1
Also called SCA3, Joseph type, Spinocerebellar ataxia type 3, Joseph type
- Body system
- Neurological diseases
- Inheritance pattern
- Autosomal dominant
- Typical age of onset
- Adult, Childhood
- Estimated prevalence
- Unknown (Worldwide)
- Rarity class
- Unknown
ORPHA:276238 is classified under "Neurological diseases" in the Orphanet nomenclature.
Common signs
- Progressive external ophthalmoplegia
- Dystonia
- Abnormality of extrapyramidal motor function
- Progressive cerebellar ataxia
- Upper motor neuron dysfunction
- Abnormal pyramidal sign