Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:636

Neurofibromatosis type 1

Also called Nonmosaic NF1, Nonmosaic neurofibromatosis type 1, Von Recklinghausen disease

Body system
Skin diseases
Inheritance pattern
Autosomal dominant
Typical age of onset
Infancy, Neonatal
Estimated prevalence
1-5 / 10 000 (United Kingdom)
Rarity class
1-5 / 10 000

ORPHA:636 is classified under "Skin diseases" in the Orphanet nomenclature.

Common signs

  • Plexiform neurofibroma
  • Lisch nodules
  • Macule
  • Neoplasm of the skin
  • Astrocytoma
  • Abnormality of the nervous system