Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:3366

Non-syndromic metopic craniosynostosis

Also called Isolated metopic craniosynostosis, Isolated trigonocephaly, Non-syndromic metopic suture synostosis

Body system
Bone diseases
Inheritance pattern
Autosomal dominant, Not applicable
Typical age of onset
Infancy, Neonatal
Estimated prevalence
1-9 / 100 000 (Europe)
Rarity class
1-9 / 100 000

ORPHA:3366 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Trigonocephaly
  • Metopic synostosis
  • Prominent supraorbital ridges
  • Narrow forehead
  • Wide nasal bridge
  • Hypotelorism