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Rare disease search prototype built on Orphanet data

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ORPHA:811

Shwachman-Diamond syndrome

Also called Pancreatic insufficiency and bone marrow dysfunction, SDS, Shwachman syndrome, Shwachman-Bodian-Diamond syndrome

Body system
Immunological diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Antenatal, Childhood, Infancy, Neonatal
Estimated prevalence
1-9 / 1 000 000 (Italy)
Rarity class
1-9 / 1 000 000

ORPHA:811 is classified under "Immunological diseases" in the Orphanet nomenclature.

Common signs

  • Abnormality of the skeletal system
  • Exocrine pancreatic insufficiency
  • Abnormality of blood and blood-forming tissues
  • Decreased total neutrophil count
  • Anemia
  • Fat malabsorption