Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:93356

Spondyloepimetaphyseal dysplasia, Missouri type

Also called SEMD type 2, SEMD, Missouri type, Spondyloepimetaphyseal dysplasia type 2

Body system
Bone diseases
Inheritance pattern
Autosomal dominant
Typical age of onset
Childhood, Infancy
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:93356 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Genu varum
  • Femoral bowing
  • Tibial bowing
  • Flared metaphysis
  • Metaphyseal irregularity
  • Flattened epiphysis