Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:3198

Stiff person spectrum disorder

Also called Moersch-Woltman syndrome, SMS, SPS, Stiff man spectrum disorder

Body system
Neurological diseases
Inheritance pattern
Not applicable
Typical age of onset
Adolescent, Adult, Childhood, Elderly, Infancy
Estimated prevalence
1-9 / 1 000 000 (Europe)
Rarity class
1-9 / 1 000 000

ORPHA:3198 is classified under "Neurological diseases" in the Orphanet nomenclature.

Common signs

  • Anxiety
  • Hyperhidrosis
  • Falls
  • EMG abnormality
  • Intermittent painful muscle spasms
  • Emotional lability