Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:331206

T-B-NK+ severe combined immunodeficiency due to complete RAG1/2 deficiency

Also called T-B-NK+ SCID due to complete RAG1/2 deficiency

Body system
Immunological diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy
Estimated prevalence
1-9 / 100 000 (Europe)
Rarity class
1-9 / 100 000

ORPHA:331206 is classified under "Immunological diseases" in the Orphanet nomenclature.

Common signs

  • Decreased circulating IgA level
  • Decreased circulating total IgM
  • Decreased circulating antibody level
  • Decreased circulating IgG level
  • Abnormal B cell count
  • Abnormal T cell count