Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:169154

T-B+NK+ severe combined immunodeficiency due to IL-7Ralpha deficiency

Also called T-B+NK+ SCID due to IL-7Ralpha deficiency

Body system
Immunological diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy
Estimated prevalence
1-9 / 1 000 000 (Worldwide)
Rarity class
1-9 / 1 000 000

ORPHA:169154 is classified under "Immunological diseases" in the Orphanet nomenclature.

Common signs

  • Recurrent infections
  • Failure to thrive
  • Lymphopenia
  • Recurrent viral infections
  • Decreased total T cell count
  • Decreased proportion of CD8-positive T cells