Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:79473

Variegate porphyria

Also called Porphyria variegata, Protoporphyrinogen oxidase deficiency

Body system
Inborn errors of metabolism
Inheritance pattern
Autosomal dominant
Typical age of onset
Adolescent, Adult
Estimated prevalence
<1 / 1 000 000 (Europe)
Rarity class
<1 / 1 000 000

ORPHA:79473 is classified under "Inborn errors of metabolism" in the Orphanet nomenclature.

Common signs

  • Abdominal pain
  • Abnormal circulating porphyrin concentration
  • Porphyrinuria
  • Increased urinary porphobilinogen
  • Abnormal enzyme/coenzyme activity
  • Abnormality of the nervous system