Rare Zebra

Rare disease search prototype built on Orphanet data

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ORPHA:1667

Wolcott-Rallison syndrome

Also called Early-onset diabetes mellitus with multiple epiphyseal dysplasia, WRS

Body system
Bone diseases
Inheritance pattern
Autosomal recessive
Typical age of onset
Infancy, Neonatal
Estimated prevalence
<1 / 1 000 000 (Worldwide)
Rarity class
<1 / 1 000 000

ORPHA:1667 is classified under "Bone diseases" in the Orphanet nomenclature.

Common signs

  • Neonatal insulin-dependent diabetes mellitus
  • Abnormality of the liver
  • Growth delay
  • Skeletal dysplasia
  • Short stature
  • Decreased total neutrophil count